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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS7
All Species:
10.61
Human Site:
S139
Identified Species:
19.44
UniProt:
O14512
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14512
NP_055413.1
581
62969
S139
C
S
E
E
E
L
S
S
P
G
R
G
G
G
G
Chimpanzee
Pan troglodytes
XP_512211
535
59559
A99
G
T
P
S
G
S
S
A
D
E
D
T
F
S
S
Rhesus Macaque
Macaca mulatta
XP_001082440
360
39867
Dog
Lupus familis
XP_548159
411
45633
S35
L
R
P
L
A
G
P
S
R
K
G
S
L
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHQ2
579
62765
S139
C
S
E
E
E
L
S
S
P
G
R
G
G
G
G
Rat
Rattus norvegicus
XP_001081372
564
60962
S125
C
S
E
E
E
L
S
S
P
G
R
G
G
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506079
518
56852
G99
G
P
A
S
L
G
S
G
D
E
D
S
F
S
S
Chicken
Gallus gallus
XP_423895
264
29931
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684929
733
79803
Q288
A
C
Q
K
P
E
S
Q
T
T
E
P
G
A
F
Tiger Blowfish
Takifugu rubipres
NP_001116335
565
61771
A111
P
S
E
A
A
A
A
A
H
L
D
V
Q
V
C
Fruit Fly
Dros. melanogaster
NP_523390
1016
110741
E233
L
G
Q
M
S
L
K
E
S
Y
A
I
N
K
H
Honey Bee
Apis mellifera
XP_397211
804
90105
T263
M
S
H
D
V
L
T
T
S
E
I
S
D
M
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792866
847
94386
D114
C
I
Y
H
N
G
C
D
I
R
N
G
N
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.6
43
69.5
N.A.
97.4
95.1
N.A.
24.1
42.6
N.A.
38.2
52.3
22
24.8
N.A.
27.8
Protein Similarity:
100
36.8
49.5
69.7
N.A.
98.1
95.8
N.A.
34.4
43.7
N.A.
48.2
62.4
32.1
39.2
N.A.
39
P-Site Identity:
100
6.6
0
6.6
N.A.
100
93.3
N.A.
6.6
0
N.A.
13.3
13.3
6.6
13.3
N.A.
20
P-Site Similarity:
100
20
0
6.6
N.A.
100
93.3
N.A.
6.6
0
N.A.
26.6
26.6
13.3
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
16
8
8
16
0
0
8
0
0
8
0
% A
% Cys:
31
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
8
0
0
0
8
16
0
24
0
8
0
0
% D
% Glu:
0
0
31
24
24
8
0
8
0
24
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
8
% F
% Gly:
16
8
0
0
8
24
0
8
0
24
8
31
31
31
16
% G
% His:
0
0
8
8
0
0
0
0
8
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
8
0
8
8
0
0
8
% I
% Lys:
0
0
0
8
0
0
8
0
0
8
0
0
0
16
0
% K
% Leu:
16
0
0
8
8
39
0
0
0
8
0
0
8
0
8
% L
% Met:
8
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
8
0
16
0
0
% N
% Pro:
8
8
16
0
8
0
8
0
24
0
0
8
0
0
0
% P
% Gln:
0
0
16
0
0
0
0
8
0
0
0
0
8
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
8
8
24
0
0
0
0
% R
% Ser:
0
39
0
16
8
8
47
31
16
0
0
24
0
16
16
% S
% Thr:
0
8
0
0
0
0
8
8
8
8
0
8
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _